Green Goblin may refer to the following:
- Goblin serum, a chemical formula created by Doctor Octopus.
- Anti-Goblin serum, a chemical formula created by Curt Connors.
- Norman Osborn, the Green Goblin from Spider-Man's universe.
- Norma Osborn, the female Green Goblin counterpart from Spider-Girl's universe.
- Ultimate Green Goblin, the Green Goblin counterpart from Miles Morales's universe.